https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Effectiveness of responses to nicotine and opiate addiction (letter) https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:4493 Wed 11 Apr 2018 10:59:49 AEST ]]> Factors associated with retention in a long-term residential rehabilitation programme for women with substance use problems https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:8209 Sat 24 Mar 2018 08:36:20 AEDT ]]> Hypogonadism in men receiving methadone and buprenorphine maintenance treatment https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7193 Sat 24 Mar 2018 08:35:44 AEDT ]]> Isolation and identification of unique marker compounds from the Tasmanian poppy Papaver somniferum N: implications for the identification of illicit heroin of Tasmanian origin https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5016 Sat 24 Mar 2018 07:44:09 AEDT ]]> Brief cognitive behavioural interventions for regular amphetamine users: a step in the right direction https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:73 Sat 24 Mar 2018 07:42:08 AEDT ]]> Cis-expression quantitative trait loci mapping reveals replicable associations with heroin addiction in OPRM1 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27149 -5): rs9478495, rs3778150, rs9384169, and rs562859. Rs3778150, located in OPRM1 intron 1, was significantly replicated (p = 6.3 x 10-5). Meta-analysis across all case-control cohorts resulted in p = 4.3 x 10-8: the rs3778150-C allele (frequency = 16%-19%) being associated with increased heroin addiction risk. Importantly, the functional SNP allele rs1799971-A was associated with heroin addiction only in the presence of rs3778150-C (p = 1.48 x 10-6 for rs1799971-A/rs3778150-C and p = .79 for rs1799971-A/rs3778150-T haplotypes). Lastly, replication was observed for six other intron 1 SNPs that had prior suggestive associations with heroin addiction (smallest p = 2.7 x 10-8 for rs3823010). Conclusions: Our findings show that common OPRM1 intron 1 SNPs have replicable associations with heroin addiction. The haplotype structure of rs3778150 and nearby SNPs may underlie the inconsistent associations between rs1799971 and heroin addiction.]]> Sat 24 Mar 2018 07:32:55 AEDT ]]> Opioid poisoning in Newcastle over the last three decades: From heroin to prescription opioids https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53531 Mon 04 Dec 2023 15:38:31 AEDT ]]>